{"id":15204,"date":"2026-08-31T16:06:18","date_gmt":"2026-08-31T09:06:18","guid":{"rendered":"https:\/\/med.siam.edu\/home2020\/?page_id=15204"},"modified":"2026-08-31T16:29:55","modified_gmt":"2026-08-31T09:29:55","slug":"research-paper","status":"publish","type":"page","link":"https:\/\/med.siam.edu\/home2020\/research-paper\/","title":{"rendered":"research paper"},"content":{"rendered":"
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\n\t\t\t\r\n\r\n\r\n \r\n \r\n \u0e1c\u0e25\u0e07\u0e32\u0e19\u0e15\u0e35\u0e1e\u0e34\u0e21\u0e1e\u0e4c - \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e2a\u0e22\u0e32\u0e21<\/title>\r\n <!-- Tailwind CSS -->\r\n <script src=\"https:\/\/cdn.tailwindcss.com\"><\/script>\r\n <!-- Lucide Icons -->\r\n <script src=\"https:\/\/unpkg.com\/lucide@latest\"><\/script>\r\n <link href=\"https:\/\/fonts.googleapis.com\/css2?family=Sarabun:wght@300;400;500;600;700&display=swap\" rel=\"stylesheet\">\r\n \r\n <style>\r\n body { \r\n font-family: 'Sarabun', sans-serif;\r\n background-color: #f8fafc;\r\n color: #334155;\r\n }\r\n\r\n \/* Layer Effects *\/\r\n .header-soft-green {\r\n background: linear-gradient(180deg, #ecfdf5 0%, #f4fbf7 60%, #f8fafc 100%);\r\n position: relative;\r\n }\r\n\r\n .header-glow {\r\n position: absolute;\r\n top: -20px;\r\n left: 50%;\r\n transform: translateX(-50%);\r\n 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box-shadow: 0 4px 12px -3px rgba(6, 78, 59, 0.25);\r\n }\r\n\r\n \/* Buttons Style *\/\r\n .btn-champagne {\r\n background: linear-gradient(135deg, #d97706 0%, #b45309 100%);\r\n color: #ffffff;\r\n font-weight: 500;\r\n box-shadow: 0 2px 8px -1px rgba(180, 83, 9, 0.25);\r\n transition: all 0.2s ease;\r\n }\r\n .btn-champagne:hover {\r\n background: linear-gradient(135deg, #f59e0b 0%, #d97706 100%);\r\n box-shadow: 0 4px 14px -1px rgba(180, 83, 9, 0.35);\r\n }\r\n\r\n .btn-soft {\r\n background: #f8fafc;\r\n color: #475569;\r\n font-weight: 500;\r\n border: 1px solid #e2e8f0;\r\n transition: all 0.2s ease;\r\n }\r\n .btn-soft:hover {\r\n background: #f1f5f9;\r\n color: #0f172a;\r\n border-color: #cbd5e1;\r\n }\r\n\r\n \/* Dropdown Style *\/\r\n .soft-dropdown {\r\n background: rgba(255, 255, 255, 0.98);\r\n backdrop-filter: blur(16px);\r\n border: 1px solid #e2e8f0;\r\n box-shadow: 0 20px 40px -10px rgba(15, 23, 42, 0.1);\r\n border-radius: 1.25rem;\r\n }\r\n\r\n \/* Pagination Style *\/\r\n .page-btn {\r\n padding: 0.5rem 0.85rem;\r\n border-radius: 0.75rem;\r\n font-size: 0.8125rem;\r\n font-weight: 500;\r\n border: 1px solid #e2e8f0;\r\n background: #ffffff;\r\n color: #475569;\r\n transition: all 0.2s ease;\r\n }\r\n .page-btn:hover:not(:disabled) {\r\n border-color: #6ee7b7;\r\n color: #065f46;\r\n background: #f0fdf4;\r\n }\r\n .page-btn.active {\r\n background: #064e3b;\r\n color: #ffffff;\r\n border-color: #064e3b;\r\n box-shadow: 0 4px 10px -2px rgba(6, 78, 59, 0.3);\r\n }\r\n .page-btn:disabled {\r\n opacity: 0.4;\r\n cursor: not-allowed;\r\n }\r\n <\/style>\r\n<\/head>\r\n<body class=\"antialiased min-h-screen pb-20\">\r\n\r\n <!-- HEADER SECTION -->\r\n <header class=\"header-soft-green border-b border-emerald-100\/70 py-14 px-6 sm:px-12\">\r\n <div class=\"header-glow\"><\/div>\r\n <div class=\"max-w-6xl mx-auto space-y-3 text-left relative z-10\">\r\n <div class=\"inline-flex items-center gap-2\">\r\n <span class=\"text-xs font-semibold uppercase tracking-widest text-emerald-700 bg-emerald-100\/70 border border-emerald-200\/50 px-3.5 py-1 rounded-full\">\r\n Faculty of Medicine, Siam University\r\n <\/span>\r\n <\/div>\r\n <h1 class=\"text-3xl sm:text-4xl font-extrabold tracking-tight text-emerald-950\">\r\n \u0e1c\u0e25\u0e07\u0e32\u0e19\u0e15\u0e35\u0e1e\u0e34\u0e21\u0e1e\u0e4c\r\n <\/h1>\r\n <p class=\"text-sm sm:text-base text-slate-600 font-normal max-w-2xl leading-relaxed\">\r\n \u0e04\u0e25\u0e31\u0e07\u0e23\u0e27\u0e1a\u0e23\u0e27\u0e21\u0e2d\u0e07\u0e04\u0e4c\u0e04\u0e27\u0e32\u0e21\u0e23\u0e39\u0e49\u0e17\u0e32\u0e07\u0e01\u0e32\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e4c \u0e07\u0e32\u0e19\u0e27\u0e34\u0e08\u0e31\u0e22\u0e04\u0e25\u0e34\u0e19\u0e34\u0e01 \u0e41\u0e25\u0e30\u0e1c\u0e25\u0e07\u0e32\u0e19\u0e15\u0e35\u0e1e\u0e34\u0e21\u0e1e\u0e4c \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e2a\u0e22\u0e32\u0e21\r\n <\/p>\r\n <\/div>\r\n <\/header>\r\n\r\n <!-- MAIN CONTAINER -->\r\n <main class=\"max-w-6xl mx-auto px-6 sm:px-12 pt-8 pb-16\">\r\n\r\n <!-- FILTER & SEARCH BAR -->\r\n <section class=\"bg-white\/70 border border-slate-200\/80 backdrop-blur-md rounded-2xl p-4 mb-6 shadow-sm\">\r\n <div class=\"flex flex-col lg:flex-row items-stretch lg:items-center justify-between gap-4\">\r\n \r\n <!-- Left Filters -->\r\n <div class=\"flex flex-wrap items-center gap-2\">\r\n <button onclick=\"resetAllFilters()\" id=\"btn-all\" class=\"tab-btn active px-4 py-2 rounded-xl text-xs tracking-wide\">\r\n \u0e17\u0e31\u0e49\u0e07\u0e2b\u0e21\u0e14\r\n <\/button>\r\n\r\n <!-- Year Dropdown -->\r\n <div class=\"relative inline-block text-left\" id=\"yearDropdownWrapper\">\r\n <button onclick=\"toggleDropdown(event, 'yearDropdownMenu', 'yearDropdownIcon')\" id=\"yearDropdownBtn\" class=\"tab-btn px-4 py-2 rounded-xl text-xs tracking-wide flex items-center gap-2\">\r\n <span id=\"selectedYearText\">\u0e1b\u0e35\u0e15\u0e35\u0e1e\u0e34\u0e21\u0e1e\u0e4c<\/span>\r\n <i data-lucide=\"chevron-down\" class=\"w-3.5 h-3.5 text-slate-400 transition-transform duration-300\" id=\"yearDropdownIcon\"><\/i>\r\n <\/button>\r\n\r\n <div id=\"yearDropdownMenu\" class=\"hidden soft-dropdown absolute left-0 mt-3 w-64 z-50 py-2 transition-all max-h-72 overflow-y-auto\">\r\n <div class=\"px-4 py-1.5 text-[10px] font-semibold text-emerald-800\/60 uppercase tracking-widest sticky top-0 bg-white\/95 backdrop-blur-md border-b border-slate-100\">\u0e1b\u0e35\u0e15\u0e35\u0e1e\u0e34\u0e21\u0e1e\u0e4c (\u0e1e.\u0e28. \/ \u0e04.\u0e28.)<\/div>\r\n <a href=\"javascript:void(0)\" onclick=\"selectYear('all')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition font-medium\">\u0e17\u0e31\u0e49\u0e07\u0e2b\u0e21\u0e14<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectYear('2026')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e1e.\u0e28. 2569 (\u0e04.\u0e28. 2026)<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectYear('2025')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e1e.\u0e28. 2568 (\u0e04.\u0e28. 2025)<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectYear('2024')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e1e.\u0e28. 2567 (\u0e04.\u0e28. 2024)<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectYear('2023')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e1e.\u0e28. 2566 (\u0e04.\u0e28. 2023)<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectYear('2022')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e1e.\u0e28. 2565 (\u0e04.\u0e28. 2022)<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectYear('2021')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e1e.\u0e28. 2564 (\u0e04.\u0e28. 2021)<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectYear('2020')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e1e.\u0e28. 2563 (\u0e04.\u0e28. 2020)<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectYear('2019')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e1e.\u0e28. 2562 (\u0e04.\u0e28. 2019)<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectYear('2018')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e1e.\u0e28. 2561 (\u0e04.\u0e28. 2018)<\/a>\r\n <a 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onclick=\"selectResearcherType('\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e2d\u0e32\u0e0a\u0e35\u0e27\u0e2d\u0e19\u0e32\u0e21\u0e31\u0e22\u0e2f')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e2d\u0e32\u0e0a\u0e35\u0e27\u0e2d\u0e19\u0e32\u0e21\u0e31\u0e22\u0e2f<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectResearcherType('\u0e19\u0e31\u0e01\u0e28\u0e36\u0e01\u0e29\u0e32\u0e41\u0e1e\u0e17\u0e22\u0e4c')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e19\u0e31\u0e01\u0e28\u0e36\u0e01\u0e29\u0e32\u0e41\u0e1e\u0e17\u0e22\u0e4c<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectResearcherType('\u0e19\u0e31\u0e01\u0e28\u0e36\u0e01\u0e29\u0e32\u0e2a\u0e32\u0e02\u0e32\u0e27\u0e34\u0e0a\u0e32\u0e2d\u0e32\u0e0a\u0e35\u0e27\u0e2d\u0e19\u0e32\u0e21\u0e31\u0e22\u0e2f')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e19\u0e31\u0e01\u0e28\u0e36\u0e01\u0e29\u0e32\u0e2a\u0e32\u0e02\u0e32\u0e27\u0e34\u0e0a\u0e32\u0e2d\u0e32\u0e0a\u0e35\u0e27\u0e2d\u0e19\u0e32\u0e21\u0e31\u0e22\u0e2f<\/a>\r\n <\/div>\r\n <\/div>\r\n\r\n <!-- Level Dropdown -->\r\n <div class=\"relative inline-block text-left\" id=\"levelDropdownWrapper\">\r\n <button onclick=\"toggleDropdown(event, 'levelDropdownMenu', 'levelDropdownIcon')\" id=\"levelDropdownBtn\" class=\"tab-btn px-4 py-2 rounded-xl text-xs tracking-wide flex items-center gap-2\">\r\n <span id=\"selectedLevelText\">\u0e23\u0e30\u0e14\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e40\u0e1c\u0e22\u0e41\u0e1e\u0e23\u0e48<\/span>\r\n <i data-lucide=\"chevron-down\" class=\"w-3.5 h-3.5 text-slate-400 transition-transform duration-300\" id=\"levelDropdownIcon\"><\/i>\r\n <\/button>\r\n\r\n <div id=\"levelDropdownMenu\" class=\"hidden soft-dropdown absolute left-0 mt-3 w-56 z-50 py-2 transition-all max-h-60 overflow-y-auto\">\r\n <div class=\"px-4 py-1.5 text-[10px] font-semibold text-emerald-800\/60 uppercase tracking-widest sticky top-0 bg-white\/95 backdrop-blur-md border-b border-slate-100\">\u0e23\u0e30\u0e14\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e40\u0e1c\u0e22\u0e41\u0e1e\u0e23\u0e48<\/div>\r\n <a href=\"javascript:void(0)\" onclick=\"selectLevel('all')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 transition\">\u0e17\u0e31\u0e49\u0e07\u0e2b\u0e21\u0e14<\/a>\r\n <a href=\"javascript:void(0)\" onclick=\"selectLevel('international')\" class=\"block px-4 py-2 text-xs text-slate-600 hover:bg-emerald-50 hover:text-emerald-800 rounded-lg mx-1 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\"Community-driven policy recommendations for dengue prevention and control in Thailand: A mixed-methods study\",\r\n authors: \"Chawarat Rotejanaprasert, Ngamphol Soonthornworasiri, Lokachet Tanasugarn, Amorn Leelarasamee, Kulkanya Chokephaibulkit, Udomsak Narkkul, Peeradone Srichan, Khuanchai Koompapong, Piroon Mootsikapun, Winai Ratanasuwan, Saranath Lawpoolsri\",\r\n researcherType: \"\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\",\r\n journal: \"Journal of Infection and Public Health (Volume 19, 2026 - Issue 4, 103166)\",\r\n year: \"2026\",\r\n type: \"international\",\r\n tag: \"Scopus, Q1\",\r\n fullTextUrl: \"https:\/\/doi.org\/10.1016\/j.jiph.2026.103166\",\r\n doi: \"10.1016\/j.jiph.2026.103166\",\r\n abstract: `Background: The World Health Organization roadmap targets the eradication of dengue, a neglected tropical disease. Community participation is crucial for successful control efforts, which must transcend technical solutions to engage and motivate the public. This study examined the needs, perceptions, and emotional drivers underpinning dengue prevention efforts and recommended tailored policies to control dengue in varied settings.\r\n\r\nMethods: This mixed-methods study, using a triangulation design, was conducted in four geographical regions of Thailand between November 2023 and April 2024. Quantitative surveys were administered to 664 community members and 430 public health personnel, complemented by 10 focus group discussions (FGDs) with community members, 16 FGDs, and 23 in-depth interviews (IDIs) with public health personnel. Logistic regression was used to examine factors associated with dengue control practices, while qualitative data were analyzed thematically. Findings from both components were integrated during interpretation to enhance the robustness of conclusions.\r\n\r\nResults: Integrated quantitative and qualitative findings showed that most participants practiced active dengue prevention. Social support strongly influenced preventive behaviors (OR 19.81; 95 % CI 8.53\u201346.03), whereas demographic factors and perceived susceptibility or severity were not significant. Higher practice levels were observed among participants in the northeast and health personnel aged \u2265 50 years. Qualitative data reinforced these findings, emphasizing the vital role of village health volunteers and challenges such as limited participation, low risk perception, poor sanitation, and cultural barriers shaping vaccine hesitancy.\r\n\r\nConclusion: Effective dengue control requires context-specific, evidence-based strategies that strengthen community participation, empower village health volunteers, and enhance vector control. Early warning systems and intersectoral collaboration are vital in high-risk areas, while transparent, culturally tailored communication can improve vaccine acceptance. These findings provide evidence to guide policy toward sustainable, community-centered dengue prevention and control.`,\r\n citationAPA: \"Rotejanaprasert, C., Soonthornworasiri, N., Tanasugarn, L., Leelarasamee, A., Chokephaibulkit, K., Narkkul, U., Srichan, P., Koompapong, K., Mootsikapun, P., Ratanasuwan, W., & Lawpoolsri, S. (2026). Community-driven policy recommendations for dengue prevention and control in Thailand: A mixed-methods study. Journal of Infection and Public Health, 19(4), 103166.\",\r\n citationVancouver: \"Rotejanaprasert C, Soonthornworasiri N, Tanasugarn L, Leelarasamee A, Chokephaibulkit K, Narkkul U, Srichan P, Koompapong K, Mootsikapun P, Ratanasuwan W, Lawpoolsri S. Community-driven policy recommendations for dengue prevention and control in Thailand: A mixed-methods study. Journal of Infection and Public Health. 2026 Feb 1;19(4):103166.\"\r\n },\r\n {\r\n id: 2,\r\n title: \"Phylogenomic analysis of a methicillin-resistant Staphylococcus aureus ST764 isolate from Thailand in global context reveals limited cross-border transmission\",\r\n authors: \"Thidarat Netikul, Bharkbhoom Jaemsai, Wuthiwat Ruangchai, Thanakron Noppanamas, Sumalee Kondo, Lalita Narachasima, Prasit Palittapongarnpim\",\r\n researcherType: \"\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\",\r\n journal: \"Microbial Genomics (Volume 12, 2026 - Issue 7, 001774)\",\r\n year: \"2026\",\r\n type: \"international\",\r\n tag: \"Scopus, Q1\",\r\n fullTextUrl: \"https:\/\/doi.org\/10.1099\/mgen.0.001774\",\r\n doi: \"10.1099\/mgen.0.001774\",\r\n abstract: `Methicillin-resistant Staphylococcus aureus (MRSA) ST764, a variant of ST5, has emerged and spread in Japan and China. We investigated the genome of a Thai isolate (SATU136) and the global phylogeny of ST764 to understand its global transmission history. The complete genome of SATU136 consists of a 2.89 Mb chromosome with a type II SCCmec element and a qacB-carrying plasmid but lacks the arginine catabolic mobile element (ACME). Based on the currently available global dataset, phylogenetic and phylodynamic analyses suggest that ST764 emerged in Japan in the early 1980s and was subsequently inferred to have disseminated to China and Thailand during the 1990s and early 2000s, coinciding with a peak in its overall effective population size. After this period, transmission was inferred to have become more geographically structured, with distinct clades forming in each country. Although cross-country transmission was inferred to be limited overall, onward dissemination to non-Asian countries was also detected within the Thailand-associated lineage. In contrast, the ACME element remained confined to a single Japanese subclade, with currently no evidence of spread beyond Japan. The relatively structured geographic distribution of ST764 offers a window for early detection upon introduction to new countries, which may facilitate control of its spread.`,\r\n citationAPA: \"Netikul, T., Jaemsai, B., Ruangchai, W., Noppanamas, T., Kondo, S., Narachasima, L., & Palittapongarnpim, P. (2026). Phylogenomic analysis of a methicillin-resistant Staphylococcus aureus ST764 isolate from Thailand in global context reveals limited cross-border transmission. Microbial Genomics, 12(7), 001774.\",\r\n citationVancouver: \"Netikul T, Jaemsai B, Ruangchai W, Noppanamas T, Kondo S, Narachasima L, Palittapongarnpim P. Phylogenomic analysis of a methicillin-resistant Staphylococcus aureus ST764 isolate from Thailand in global context reveals limited cross-border transmission. Microbial Genomics. 2026 Jul 16;12(7):001774.\"\r\n },\r\n {\r\n id: 3,\r\n title: \"RGD-functionalized cannabidiol lipid nanoparticles improve brain delivery and alleviate cognitive and metabolic dysfunction via gut-brain axis modulation in an Alzheimer's disease model\",\r\n authors: \"Sarawut Lapmanee, Natchayaporn Thonapan, Siriwan Sriwong, Sakkarin Bhubhanil, Prapimpun Wongchitrat, Natthawut Charoenphon, Thitaphat Ngernsutivorakul, Khemmaphat Hooncharoen, Phichaporn Bunwatcharaphansakun, Mattaka Khongkow, Katawut Namdee\",\r\n researcherType: \"\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\",\r\n journal: \"Biomedicine & Pharmacotherapy (Volume 201, 2026, 119724)\",\r\n year: \"2026\",\r\n type: \"international\",\r\n tag: \"Scopus, Q1\",\r\n fullTextUrl: \"https:\/\/doi.org\/10.1016\/j.biopha.2026.119724\",\r\n doi: \"10.1016\/j.biopha.2026.119724\",\r\n abstract: `Alzheimer's disease (AD) is a progressive neurodegenerative disorder closely associated with metabolic dysfunction and dysbiosis along the gut-brain axis. Effective therapeutic strategies targeting both central and peripheral pathologies remain limited due to poor drug permeability across the blood-brain barrier (BBB). \r\n\r\nIn this study, Arg-Gly-Asp (RGD)-functionalized lipid nanoparticles loaded with cannabidiol (CBD-RGD-LNPs) were developed to enhance brain-targeted delivery and mitigate AD-like symptoms. The formulation demonstrated high entrapment efficiency, sustained drug release, and enhanced cellular uptake in BBB endothelial models via integrin-mediated endocytosis. In vivo evaluations in an AD mouse model revealed that oral or systemic administration of CBD-RGD-LNPs significantly improved spatial learning, memory deficits, and metabolic parameters compared to free CBD. \r\n\r\nMechanistically, CBD-RGD-LNPs effectively attenuated neuroinflammation, suppressed amyloid-beta accumulation, restored gut microbiota diversity, and normalized gut barrier integrity. These findings highlight the potential of RGD-functionalized nanocarriers for targeted CBD delivery to simultaneously modulate gut-brain axis dysfunction and cognitive decline in AD.`,\r\n citationAPA: \"Lapmanee, S., Thonapan, N., Sriwong, S., Bhubhanil, S., Wongchitrat, P., Charoenphon, N., Ngernsutivorakul, T., Hooncharoen, K., Bunwatcharaphansakun, P., Khongkow, M., & Namdee, K. (2026). RGD-functionalized cannabidiol lipid nanoparticles improve brain delivery and alleviate cognitive and metabolic dysfunction via gut-brain axis modulation in an Alzheimer's disease model. Biomedicine & Pharmacotherapy, 201, 119724.\",\r\n citationVancouver: \"Lapmanee S, Thonapan N, Sriwong S, Bhubhanil S, Wongchitrat P, Charoenphon N, Ngernsutivorakul T, Hooncharoen K, Bunwatcharaphansakun P, Khongkow M, Namdee K. RGD-functionalized cannabidiol lipid nanoparticles improve brain delivery and alleviate cognitive and metabolic dysfunction via gut-brain axis modulation in an Alzheimer's disease model. Biomed Pharmacother. 2026 Aug 1;201:119724.\"\r\n },\r\n {\r\n id: 4,\r\n title: \"Development of piperine\/HP\u03b2CD-loaded PVA-coated iron oxide nanoparticles in in situ gel for enhanced retinal delivery and anti-VEGF activity\",\r\n authors: \"Phatsawee Jansook, Hay Man Saung Hnin Soe, Theingi Tun, Hay Marn Hnin, Supakarn Chamni, Rathapon Asasutjarit, Sarawut Lapmanee, Narumol Bhummaphan, Charoenchai Puttipanyalears, Sakkarin Bhubhanil, Anjaree Inchan, Natthawut Charoenphon, Yi Lu, Wei Wu\",\r\n researcherType: \"\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\",\r\n journal: \"European Journal of Pharmaceutics and Biopharmaceutics (Volume 218, 2026 - 114931)\",\r\n year: \"2025\",\r\n type: \"international\",\r\n tag: \"Scopus, Q1\",\r\n fullTextUrl: \"https:\/\/doi.org\/10.1016\/j.ejpb.2025.114931\",\r\n doi: \"10.1016\/j.ejpb.2025.114931\",\r\n abstract: `Piperine (PIP) is a potential therapeutic agent for retinal diseases; however, its poor aqueous solubility limits its ocular bioavailability. To overcome this limitation, a novel nanocarrier system was fabricated through the adsorption of PIP\/hydroxypropyl-\u03b2-cyclodextrin (HP\u03b2CD) inclusion complexes onto the surface of polymer-stabilized iron oxide nanoparticles (IONs), which were then incorporated into an in situ gelling formulation. Three hydrophilic polymers, i.e., polyethylene glycol, poloxamer 407, and polyvinyl alcohol (PVA) were used as surface coatings. Among these, PIP\/HP\u03b2CD\/PVA-IONs exhibited the highest percent entrapment efficiency (77.38 \u00b1 2.17 %) and superior mucoadhesive properties. Ocular safety was evaluated using the hen\u2019s egg test on chorioallantoic membrane (HET-CAM), which indicated no irritation. To further enhance ocular retention and retinal delivery, the PIP\/HP\u03b2CD\/PVA-IONs were incorporated into an in situ gel. Upon contact with simulated tear fluid, the formulation underwent a sol-to-gel transition with excellent gelling capacity and improved ex vivo permeation across excised porcine cornea (0.85 \u00b1 0.07 \u00d7 10-6 cm\u22c5s\u22121) and sclera (3.16 \u00b1 0.29 \u00d7 10-6 cm\u22c5s\u22121). In vitro studies on ARPE-19 retinal cells demonstrated the formulation was non-toxic at concentrations up to 50 \u00b5g\/mL (>70 % cell viability). Furthermore, in vitro and in vivo evaluations revealed that the formulation effectively suppressed vascular endothelial growth factor A at both the protein and mRNA levels. It also exhibited significant anti-inflammatory and anti-angiogenic effects. These findings suggest that the PIP\/HP\u03b2CD-loaded IONs incorporated in in situ gel system offers a promising nanocarrier platform for targeted ocular drug delivery in the treatment of retinal diseases.`,\r\n citationAPA: \"Jansook, P., Soe, H. M. S. H., Tun, T., Hnin, H. M., Chamni, S., Asasutjarit, R., Lapmanee, S., Bhummaphan, N., Puttipanyalears, C., Bhubhanil, S., Inchan, A., Charoenphon, N., Lu, Y., & Wu, W. (2025). Development of piperine\/HP\u03b2CD-loaded PVA-coated iron oxide nanoparticles in in situ gel for enhanced retinal delivery and anti-VEGF activity. European Journal of Pharmaceutics and Biopharmaceutics, 114931.\",\r\n citationVancouver: \"Jansook P, Soe HM, Tun T, Hnin HM, Chamni S, Asasutjarit R, Lapmanee S, Bhummaphan N, Puttipanyalears C, Bhubhanil S, Inchan A, Charoenphon N, Lu Y, Wu W. Development of piperine\/HP\u03b2CD-loaded PVA-coated iron oxide nanoparticles in in situ gel for enhanced retinal delivery and anti-VEGF activity. European Journal of Pharmaceutics and Biopharmaceutics. 2025 Nov 8:114931.\"\r\n },\r\n {\r\n id: 5,\r\n title: \"Transfersomal delivery of Centella asiatica promotes efficient excision wound healing in rats\",\r\n authors: \"Sarawut Lapmanee, Phichaporn Bunwatcharaphansakun, Waleewan Phongsupa, Katawut Namdee, Khomson Suttisintong, Udom Asawapirom, Uracha Ruktanonchai, Prapimpun Wongchitrat, Sakkarin Bhubhanil, Phornphimon Maitarad, Mattaka Khongkow\",\r\n researcherType: \"\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\",\r\n journal: \"Drug Delivery (Volume 32, 2025 - Issue 1, 2563649)\",\r\n year: \"2025\",\r\n type: \"international\",\r\n tag: \"Scopus, Q1 TOP10\",\r\n fullTextUrl: \"https:\/\/doi.org\/10.1080\/10717544.2025.2563649\",\r\n doi: \"10.1080\/10717544.2025.2563649\",\r\n abstract: `This study presents the development and evaluation of Centella Asiatica (CA)-loaded transfersomes (CANP) as a novel nanocarrier for transdermal delivery. CANP were prepared using an oil-in-water emulsion method, producing nanoparticles with a size of 135.22 \u00b1 4.80 nm, a polydispersity index of 0.22 \u00b1 0.01, and a zeta potential of \u221226.13 \u00b1 0.58 mV. Stability tests confirmed consistent physicochemical properties under various storage conditions, with encapsulation efficiencies above 68% for madecassoside and 89% for asiaticoside. Ex vivo permeation studies using porcine skin showed significantly improved skin penetration compared to liposomes and niosomes, attributed to the high deformability index (1.31 \u00b1 0.21 mg\/cm2). In vitro cytotoxicity assays indicated cell viability above 80% across concentrations. Functionally, CANP reduced nitric oxide production in LPS-stimulated RAW 264.7 cells, demonstrating superior anti-inflammatory effects over native CA. CANP also promoted fibroblast proliferation and collagen production by 91.9% and 213.3% at days 7 and 14, respectively, exceeding vitamin C. Wound healing assays confirmed enhanced fibroblast migration and closure rates similar to fibroblast growth factor. In vivo, CANP hydrogels accelerated healing, with early fibroblast activity and collagen deposition between days 7\u201314, supporting epithelial regeneration over 21 days. Compared to controls, they more effectively reduced inflammation and increased dermal growth factor expression. These findings support CANP as a promising transdermal nanocarrier with enhanced skin penetration, anti-inflammatory activity, and regenerative potential. Encapsulating CA into transfersomes boosts its therapeutic efficacy, making it a strong candidate for advanced dermal applications.`,\r\n citationAPA: \"Lapmanee, S., Bunwatcharaphansakun, P., Phongsupa, W., Namdee, K., Suttisintong, K., Asawapirom, U., Ruktanonchai, U., Wongchitrat, P., Bhubhanil, S., Maitarad, P., & Khongkow, M. (2025). Transfersomal delivery of Centella asiatica promotes efficient excision wound healing in rats. Drug Delivery, 32(1), 2563649.\",\r\n citationVancouver: \"Lapmanee S, Bunwatcharaphansakun P, Phongsupa W, Namdee K, Suttisintong K, Asawapirom U, Ruktanonchai U, Wongchitrat P, Bhubhanil S, Maitarad P, Khongkow M. Transfersomal delivery of Centella asiatica promotes efficient excision wound healing in rats. Drug Delivery. 2025 Dec 31;32(1):2563649.\"\r\n },\r\n {\r\n id: 6,\r\n title: \"Topographic Anatomy of the Blood Vessels in Anterior Abdominal Wall Implicating to Avoid the Vascular Complications in Lower Abdominal Liposuction: Computed Tomography Angiography\",\r\n authors: \"Chalermquan Na Pattalung, Siriporn Thanamee, Sataporn Charoensuk, Wiwat Jorakit, Amonrut Yuenyongwattanakul, Sukanya Uruwan, Tanvaa Tansatit\",\r\n researcherType: \"\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\",\r\n journal: \"Christian University Journal (Volume 31, 2025 - Issue 1, 91\u2013105)\",\r\n year: \"2025\",\r\n type: \"national\",\r\n tag: \"TCI 1\",\r\n fullTextUrl: \"https:\/\/he01.tci-thaijo.org\/index.php\/CUTJ\/article\/view\/272968\",\r\n doi: \"N\/A\",\r\n abstract: `The liposuction has become a popularly performed aesthetic procedure. It is continuously invented and developed for effective results. However, bleeding from a vascular injury during the procedure can become a major problem, such as hypovolemic shock. There are still few studies of blood vessels related to abdominal liposuction. And the location of these abdominal blood vessels is close to the procedure point. As a result, vascular injuries may occur. \r\n\r\nThis study was investigated in the blood vessels of the lower abdomen and upper thighs by computed tomography angiography (CTA). From the vascular images of CTA in 100 hemi-abdomens without vascular pathology, anatomical information was studied. It was found that the superficial inferior epigastric artery originated 47.81\u00b13.80 mm below the anterior superior iliac spine (ASIS) of the hip bone. It was positioned in relation to the inner vertical axis that divided the abdomen into three regions (Y1), ranging from -1.64 to +4.14 mm. The deep artery entered the rectus sheath at 1.97\u00b11.14 mm medial to the Y1 axis and was 4.19\u00b12.64 mm lower than the ASIS with an average diameter of 2.12\u00b11.75 mm. \r\n\r\nFinally, this anatomical knowledge is beneficial for aesthetic physicians to ascertain the blood vessels. Therefore, vascular complications during abdominal liposuction can be avoided.`,\r\n citationAPA: \"Na Pattalung, C., Thanamee, S., Charoensuk, S., Jorakit, W., Yuenyongwattanakul, A., Uruwan, S., & Tansatit, T. (2025). Topographic Anatomy of the Blood Vessels in Anterior Abdominal Wall Implicating to Avoid the Vascular Complications in Lower Abdominal Liposuction: Computed Tomography Angiography. Christian University Journal, 31(1), 91-105.\",\r\n citationVancouver: \"Na Pattalung C, Thanamee S, Charoensuk S, Jorakit W, Yuenyongwattanakul A, Uruwan S, Tansatit T. Topographic Anatomy of the Blood Vessels in Anterior Abdominal Wall Implicating to Avoid the Vascular Complications in Lower Abdominal Liposuction: Computed Tomography Angiography. Christian University Journal. 2025 Mar 20;31(1):91-105.\"\r\n },\r\n {\r\n id: 7,\r\n title: \"Oral andrographolide loaded lipid nanocarriers alleviate stress behaviors and hippocampal damage in TNF alpha induced neuroinflammatory mice\",\r\n authors: \"Sarawut Lapmanee, Natchanon Rimsueb, Phichaporn Bunwatcharaphansakun, Katawut Namdee, Prapimpun Wongchitrat, Sakkarin Bhubhanil, Nattapon Supkamonseni, Natthawut Charoenphon, Anjaree Inchan, Rattaporn Saenmuangchin, Mattaka Khongkow\",\r\n researcherType: \"\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\",\r\n journal: \"Scientific Reports (volume 15, 2025 - Article number: 11939)\",\r\n year: \"2025\",\r\n type: \"international\",\r\n tag: \"Scopus, Q1\",\r\n fullTextUrl: \"https:\/\/doi.org\/10.1038\/s41598-025-96758-1\",\r\n doi: \"10.1038\/s41598-025-96758-1\",\r\n abstract: `This study aimed to improve the delivery efficacy of andrographolide (Andro) by encapsulating it in nanostructured lipid carriers (NLCs) and to evaluate its effectiveness in reducing systemic inflammation. These AndroNLCs exhibited homogeneity with a particle size of 131.40 \u00b1 1.30 nm and approximately 89% encapsulation efficiency. AndroNLCs potentially enhanced oral efficacy by improving gastrointestinal stability, with reduced toxicity and inflammation in SH-SY5Y neuroblastoma cells. Inflammation was induced in sexually active C57BL\/6 male mice with five intraperitoneal doses of 63 \u00b5g\/kg TNF-alpha every three days. This was accompanied by daily oral administration of 10 mg\/kg AndroNLCs, venlafaxine, or 1 mg\/kg dexamethasone for 14 days. Mice with TNF-alpha-induced inflammation showed sickness signs and abnormal behaviors, assessed via physical changes, anxiety and depression tests (i.e., open field, elevated-T maze, tail suspension, and forced swimming), and biochemical assays. These changes included weight loss and compensatory responses to inflammation, as indicated by increased immune- and stress-modulated organ weights, elevated serum corticosterone levels, altered liver function markers, and higher levels of hippocampal IL-6 and TNF-alpha. Furthermore, histological analysis showed pyknotic cells, reduced layer thickness, and decreased hippocampal cell survival. Conversely, AndroNLCs significantly improved stress- and inflammation-related markers, alleviated behavioral abnormalities, reduced liver toxicity, and restored hippocampal morphology, showing effects greater than Andro alone and comparable to traditional treatments. These findings suggest that AndroNLCs have therapeutic effects on neuroinflammation but may risk contributing to mood disorders.`,\r\n citationAPA: \"Lapmanee, S., Rimsueb, N., Bunwatcharaphansakun, P., Namdee, K., Wongchitrat, P., Bhubhanil, S., ... & Khongkow, M. (2025). Oral andrographolide loaded lipid nanocarriers alleviate stress behaviors and hippocampal damage in TNF alpha induced neuroinflammatory mice. Scientific Reports, 15(1), 11939.\",\r\n citationVancouver: \"Lapmanee S, Rimsueb N, Bunwatcharaphansakun P, Namdee K, Wongchitrat P, Bhubhanil S, Supkamonseni N, Charoenphon N, Inchan A, Saenmuangchin R, Khongkow M. Oral andrographolide loaded lipid nanocarriers alleviate stress behaviors and hippocampal damage in TNF alpha induced neuroinflammatory mice. Scientific Reports. 2025 Apr 8;15(1):11939.\"\r\n },\r\n {\r\n id: 8,\r\n title: \"Application of Gelatin\/Vanillin\/Fe3+\/AGP\u2013AgNPs Hydrogels Promotes Wound Contraction, Enhances Dermal Growth Factor Expression, and Minimizes Skin Irritation\",\r\n authors: \"Sarawut Lapmanee, Sakkarin Bhubhanil, Mattaka Khongkow, Katawut Namdee, Werayut Yingmema, Narumol Bhummaphan, Prapimpun Wongchitrat, Natthawut Charoenphon, James A. Hutchison, Chanon Talodthaisong, Sirinan Kulchat\",\r\n researcherType: \"\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\",\r\n journal: \"ACS Omega (Volume 10, 2025 - Issue 10, 10530)\",\r\n year: \"2025\",\r\n type: \"international\",\r\n tag: \"Scopus, Q1\",\r\n fullTextUrl: \"https:\/\/doi.org\/10.1021\/acsomega.4c10648\",\r\n doi: \"10.1021\/acsomega.4c10648\",\r\n abstract: `This study further investigates the potential of gelatin-based hydrogel cross-linked with vanillin and ferric ion (GVF), combined with andrographolide (AGP) and silver nanoparticles (AgNPs), as an anti-infection biomaterial for wound dressing, aimed at exploring the mechanisms that attenuate inflammation, enhance wound healing rates, and address allergic skin irritation. AGP\u2013AgNPs were evaluated for cytotoxicity in human adult epidermal keratinocytes (HEKa) and the murine macrophage cell line (RAW 264.7), as well as for nitric oxide (NO) production in response to lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells. Skin-wound specimens from male Wistar rats were histologically analyzed for epidermal thickness and inflammatory changes. The mRNA expression profiling of dermal growth factors was assessed using RT-qPCR, and skin irritation tests were conducted in female New Zealand rabbits. These AGP\u2013AgNPs exhibited significantly lower toxicity in HEKa and no toxicity in RAW 264.7. Interestingly, AGP\u2013AgNPs at specific concentrations produced NO in RAW 264.7 control cells but were more effective in reducing inflammatory NO levels in RAW 264.7 cells pretreated with lipopolysaccharides, suggesting that AGP\u2013AgNP composites are safe and effectively diminish inflammation. Furthermore, a marked increase in epidermal thickness and a reduction in histological inflammatory cells at wound sites were observed in rats treated with AGP\u2013AgNPs\/GVF hydrogels over 21 days. Upregulation of dermal genes promoting wound healing, including collagen types I and III, epidermal growth factor, transforming growth factor-beta, fibronectin, and vascular endothelial growth factor, but not fibroblast growth factor, was observed in a time-dependent manner. These results suggest that the anti-inflammatory properties of GVF\/AGP\u2013AgNP hydrogels could promote epithelialization, enhance cellular proliferation, support extracellular matrix synthesis, and facilitate angiogenesis. Additionally, rabbit skin in contact with GVF\/AGP\u2013AgNP hydrogels consistently displayed reduced levels of erythema and edema, with no swelling, and a standardized scoring system yielded low primary dermal irritation indices for this hydrogel. These findings suggest that the novel GVF\/AGP\u2013AgNP hydrogels possess anti-inflammatory-like activity and can modulate dermal growth factors for wound healing. This leads to reduced dermal irritation, making the formulation potentially suitable for safe topical applications in skin and wound care. However, comprehensive human studies and clinical trials should be required in the future.`,\r\n citationAPA: \"Lapmanee, S., Bhubhanil, S., Khongkow, M., Namdee, K., Yingmema, W., Bhummaphan, N., ... & Kulchat, S. (2025). Application of gelatin\/vanillin\/Fe3+\/agp\u2013agnps hydrogels promotes wound contraction, enhances dermal growth factor expression, and minimizes skin irritation. ACS omega, 10(10), 10530.\",\r\n citationVancouver: \"Lapmanee S, Bhubhanil S, Khongkow M, Namdee K, Yingmema W, Bhummaphan N, Wongchitrat P, Charoenphon N, Hutchison JA, Talodthaisong C, Kulchat S. Application of gelatin\/vanillin\/Fe3+\/agp\u2013agnps hydrogels promotes wound contraction, enhances dermal growth factor expression, and minimizes skin irritation. ACS omega. 2025 Mar 4;10(10):10530.\"\r\n },\r\n {\r\n id: 9,\r\n title: \"Developing Attitudes Toward Medical Professionalism: the 10 Virtues of The King Principle through Group Discussion Learning Among Second-Year Medical Students in Medical Ethics\",\r\n authors: \"Kittisak Sinphitukkul\",\r\n researcherType: \"\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\",\r\n journal: \"Journal of Education and Innovative Learning (Volume 4, 2024 - Issue 2, 161-175)\",\r\n year: \"2024\",\r\n type: \"national\",\r\n tag: \"TCI 1\",\r\n fullTextUrl: \"https:\/\/so06.tci-thaijo.org\/index.php\/jeil\/article\/view\/267807\",\r\n doi: \"N\/A\",\r\n abstract: `The objective of this research was to compare the mean scores of attitudes toward medical professionalism before and after teaching the 10 virtues of the King principle through group discussion learning. Additionally, the study aimed to apply those 10 virtues of the King leading to the development of attitudes toward medical professionalism from the perspective of second-year medical students. The target population consisted of 48 second-year medical students during the first semester of the academic year 2022, at Siam University. The research utilized a one-group pretest-posttest quasi-experimental design, involving the development of activities and creation of teaching tools. The instruments used collected data on the attitudes towards medical professionalism questionnaire and focus group discussion. The results were analyzed by descriptive statistics. The results of the study showed that the mean scores for attitudes toward medical professionalism in all aspects were 171.2\u00b112.1 before learning and 182.5\u00b19.2 after learning. The percentage of learner development was recorded as high, at 52.5%. From the perspective of medical students, 6 of the 10 virtues of the King principle are charity, sacrifice, honesty, gentleness, perseverance, and non-violence, and these virtues contribute to the development of attitudes toward medical professionalism. Therefore, teaching about medical professionalism in the form of discussing the 10 virtues of the King principle through group discussion aids in developing proper attitudes for medical professionalism among second-year medical students.`,\r\n citationAPA: \"Sinphitukkul, K. (2024). Developing Attitudes Toward Medical Professionalism: the 10 Virtues of The King Principle through Group Discussion Learning Among Second-Year Medical Students in Medical Ethics. Journal of Education and Innovative Learning, 4(2), 161-175.\",\r\n citationVancouver: \"Sinphitukkul K. Developing Attitudes Toward Medical Professionalism: the 10 Virtues of The King Principle through Group Discussion Learning Among Second-Year Medical Students in Medical Ethics. Journal of Education and Innovative Learning. 2024 Aug 26;4(2):161-175.\"\r\n },\r\n {\r\n id: 10,\r\n title: \"Cannabidiol-Loaded Lipid Nanoparticles Incorporated in Polyvinyl Alcohol and Sodium Alginate Hydrogel Scaffold for Enhancing Cell Migration and Accelerating Wound Healing\",\r\n authors: \"Sarawut Lapmanee, Sakkarin Bhubhanil, Natthawut Charoenphon, Anjaree Inchan, Phichaporn Bunwatcharaphansakun, Mattaka Khongkow, Katawut Namdee\",\r\n researcherType: \"\u0e2d\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c\u0e2b\u0e25\u0e31\u0e01\u0e2a\u0e39\u0e15\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\",\r\n journal: \"Gels (Volume 10, 2024 - Issue 12, 843)\",\r\n year: \"2024\",\r\n type: \"international\",\r\n tag: \"Scopus, Q2\",\r\n fullTextUrl: \"https:\/\/doi.org\/10.3390\/gels10120843\",\r\n doi: \"10.3390\/gels10120843\",\r\n abstract: `Chronic wounds represent a persistent clinical challenge due to prolonged inflammation and impaired tissue repair mechanisms. Cannabidiol (CBD), recognized for its anti-inflammatory and pro-healing properties, shows therapeutic promise in wound care. However, its delivery via lipid nanoparticles (LNPs) remains challenging due to CBD\u2019s inherent instability and low bioavailability. This study developed and characterized a novel hydrogel scaffold composed of CBD-loaded LNPs (CBD\/LNPs) integrated into a polyvinyl alcohol (PVA) and sodium alginate (SA) matrix, designed to enhance wound repair and mitigate inflammation. The characteristics of the hydrogel scaffold were observed including the degree of swelling and LNPs\u2019 release profiles. Furthermore, in the results, CBD\/LNPs displayed enhanced stability and reduced cytotoxicity compared to unencapsulated CBD. In vitro assays demonstrated that CBD\/LNPs significantly promoted fibroblast migration in gap-closure wound models and reduced intracellular reactive oxygen species, supporting their potential as a biocompatible and efficacious agent for cellular repair and oxidative stress attenuation. In vivo experiments using adult male Wistar rats with aseptic cutaneous wounds revealed that treatment with CBD\/LNP-PVA\/SA hydrogel scaffold significantly accelerated wound closure relative to blank hydrogel controls, demonstrating a substantial reduction in the wound area over time. Histological analysis confirms notable improvements in skin morphology in wounds treated with CBD\/LNP-PVA\/SA hydrogel scaffold with evidence of accelerated epithelialization, enhanced collagen deposition, and increased dermal thickness and vascularization. Additionally, skin histology showed a more organized epidermal layer and reduced inflammatory cell infiltration in CBD\/LNP-PVA\/SA hydrogel scaffold-treated wounds, corresponding to a 35% increase in the wound closure rate by day 28 post-treatment. These findings suggest that CBD\/LNP-PVA\/SA hydrogel scaffolds facilitate inflammation resolution and structural wound healing through localized, sustained CBD delivery. The dual anti-inflammatory and wound-healing effects position CBD\/LNP-PVA\/SA hydrogel scaffold as a promising approach for chronic wound management. Future investigations are warranted to elucidate the mechanistic pathways by which CBD modulates the skin architecture and to explore its translational applications in clinical wound care.`,\r\n citationAPA: \"Lapmanee, S., Bhubhanil, S., Charoenphon, N., Inchan, A., Bunwatcharaphansakun, P., Khongkow, M., & Namdee, K. (2024). Cannabidiol-loaded lipid nanoparticles incorporated in polyvinyl alcohol and sodium alginate hydrogel scaffold for enhancing cell migration and accelerating wound healing. Gels, 10(12), 843.\",\r\n citationVancouver: \"Lapmanee S, Bhubhanil S, Charoenphon N, Inchan A, Bunwatcharaphansakun P, Khongkow M, Namdee K. Cannabidiol-loaded lipid nanoparticles incorporated in polyvinyl alcohol and sodium alginate hydrogel scaffold for enhancing cell migration and accelerating wound healing. Gels. 2024 Dec 20;10(12):843.\"\r\n }\r\n ];\r\n\r\n let currentLevel = 'all'; \r\n let currentYear = 'all';\r\n let currentResearcherType = 'all';\r\n let currentSearch = '';\r\n let selectedItemForCitation = null;\r\n let selectedItemForAbstract = null;\r\n let activeCitationFormat = 'APA';\r\n\r\n \/\/ Variable \u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e23\u0e30\u0e1a\u0e1a Pagination\r\n let currentPage = 1;\r\n const itemsPerPage = 7;\r\n\r\n function renderData() {\r\n const query = currentSearch.toLowerCase().trim();\r\n\r\n const filteredData = allResearch.filter(item => {\r\n const matchLevel = (currentLevel === 'all') || (item.type === currentLevel);\r\n const matchYear = (currentYear === 'all') || (item.year === currentYear);\r\n const matchResearcher = (currentResearcherType === 'all') || (item.researcherType === currentResearcherType);\r\n \r\n const matchSearch = query === '' || \r\n item.title.toLowerCase().includes(query) || \r\n item.authors.toLowerCase().includes(query) ||\r\n item.researcherType.toLowerCase().includes(query) ||\r\n item.journal.toLowerCase().includes(query) ||\r\n item.doi.toLowerCase().includes(query) ||\r\n item.fullTextUrl.toLowerCase().includes(query);\r\n\r\n return matchLevel && matchYear && matchResearcher && matchSearch;\r\n });\r\n\r\n \/\/ \u0e04\u0e33\u0e19\u0e27\u0e13\u0e02\u0e49\u0e2d\u0e21\u0e39\u0e25 Pagination\r\n const totalItems = filteredData.length;\r\n const totalPages = Math.ceil(totalItems \/ itemsPerPage);\r\n\r\n if (currentPage > totalPages && totalPages > 0) {\r\n currentPage = totalPages;\r\n } else if (currentPage < 1) {\r\n currentPage = 1;\r\n }\r\n\r\n const startIndex = (currentPage - 1) * itemsPerPage;\r\n const endIndex = Math.min(startIndex + itemsPerPage, totalItems);\r\n const paginatedData = filteredData.slice(startIndex, endIndex);\r\n\r\n \/\/ \u0e2d\u0e31\u0e1b\u0e40\u0e14\u0e15\u0e15\u0e31\u0e27\u0e40\u0e25\u0e02\u0e41\u0e2a\u0e14\u0e07\u0e1c\u0e25\r\n document.getElementById('showingCount').innerText = totalItems > 0 ? 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document.getElementById('modalContentCitation');\r\n content.classList.remove('scale-100', 'opacity-100');\r\n content.classList.add('scale-95', 'opacity-0');\r\n setTimeout(() => { modal.classList.add('hidden'); }, 200);\r\n }\r\n\r\n function switchCitationFormat(format) {\r\n activeCitationFormat = format;\r\n const tabApa = document.getElementById('tab-apa');\r\n const tabVan = document.getElementById('tab-vancouver');\r\n if (format === 'APA') {\r\n tabApa.className = \"px-3.5 py-1.5 text-xs font-semibold rounded-xl bg-emerald-100 text-emerald-800 transition\";\r\n tabVan.className = \"px-3.5 py-1.5 text-xs font-semibold rounded-xl bg-slate-100 text-slate-600 hover:bg-slate-200 transition\";\r\n } else {\r\n tabVan.className = \"px-3.5 py-1.5 text-xs font-semibold rounded-xl bg-emerald-100 text-emerald-800 transition\";\r\n tabApa.className = \"px-3.5 py-1.5 text-xs font-semibold rounded-xl bg-slate-100 text-slate-600 hover:bg-slate-200 transition\";\r\n }\r\n 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<\/script>\r\n<\/body>\r\n<\/html>\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"\u0e1c\u0e25\u0e07\u0e32\u0e19\u0e15\u0e35\u0e1e\u0e34\u0e21\u0e1e\u0e4c - \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e2a\u0e22\u0e32\u0e21 Faculty of Medicine, Siam University \u0e1c\u0e25\u0e07\u0e32\u0e19\u0e15\u0e35\u0e1e\u0e34\u0e21\u0e1e\u0e4c \u0e04\u0e25\u0e31\u0e07\u0e23\u0e27\u0e1a\u0e23\u0e27\u0e21\u0e2d\u0e07\u0e04\u0e4c\u0e04\u0e27\u0e32\u0e21\u0e23\u0e39\u0e49\u0e17\u0e32\u0e07\u0e01\u0e32\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e4c \u0e07\u0e32\u0e19\u0e27\u0e34\u0e08\u0e31\u0e22\u0e04\u0e25\u0e34\u0e19\u0e34\u0e01 \u0e41\u0e25\u0e30\u0e1c\u0e25\u0e07\u0e32\u0e19\u0e15\u0e35\u0e1e\u0e34\u0e21\u0e1e\u0e4c \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e2a\u0e22\u0e32\u0e21 \u0e17\u0e31\u0e49\u0e07\u0e2b\u0e21\u0e14 \u0e1b\u0e35\u0e15\u0e35\u0e1e\u0e34\u0e21\u0e1e\u0e4c \u0e1b\u0e35\u0e15\u0e35\u0e1e\u0e34\u0e21\u0e1e\u0e4c (\u0e1e.\u0e28. \/ \u0e04.\u0e28.) \u0e17\u0e31\u0e49\u0e07\u0e2b\u0e21\u0e14 \u0e1e.\u0e28. 2569 (\u0e04.\u0e28. 2026) \u0e1e.\u0e28. 2568 (\u0e04.\u0e28. 2025) \u0e1e.\u0e28. 2567 (\u0e04.\u0e28. 2024) \u0e1e.\u0e28. 2566 (\u0e04.\u0e28. 2023) \u0e1e.\u0e28. 2565 <a href=\"https:\/\/med.siam.edu\/home2020\/research-paper\/\" class=\"read-more\">Read More ...<\/a>","protected":false},"author":243,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-15204","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>research 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